Structured Summary
Abstract
A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
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Classification
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MeSH Record
Synonyms
19 entry terms
- ADP Ribose Cyclase
- ADPR Cyclase
- Adenosine Diphosphate Ribose Cyclase
- ADP ribosyl Cyclase
- Cyclase, ADP Ribose
- Cyclase, ADP-ribosyl
- Cyclase, ADPR
- Ribose Cyclase, ADP
- 2'-P-ADPR Cyclase
- 2'-Phospho-adenosine Diphosphate Ribose Cyclase
- Cyclic ADP-ribose Hydrolase
- cADPR Hydrolase
- 2' P ADPR Cyclase
- 2' Phospho adenosine Diphosphate Ribose Cyclase
- ADP-ribose Hydrolase, Cyclic
- Cyclase, 2'-P-ADPR
- Cyclic ADP ribose Hydrolase
- Hydrolase, Cyclic ADP-ribose
- Hydrolase, cADPR
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003; use CD38 ANTIGEN (NM) 1988-2002
MeSH Record
Previous Indexing
- Antigens, Differentiation (1991-2002)
- NAD+ Nucleosidase (1993-2002)
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AMA Style
References
- National Library of Medicine. ADP-ribosyl Cyclase. Medical Subject Headings (MeSH). 2026. Unique ID D036541. http://id.nlm.nih.gov/mesh/2026/D036541
- ADP-ribosyl Cyclase. In: Wikidata. https://www.wikidata.org/wiki/Q24775708