Structured Summary
Abstract
A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.
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Classification
Broader headings
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MeSH Record
Synonyms
10 entry terms
- ADAM 12 Protein
- ADAM-12 Protein
- Disintegrin and Metalloproteinase Domain-Containing Protein 12
- Meltrin-alpha Protein
- Disintegrin and Metalloproteinase Domain Containing Protein 12
- Meltrin alpha Protein
- ADAM12-L Protein
- ADAM12-S Protein
- ADAM12 L Protein
- ADAM12 S Protein
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1997)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. ADAM12 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000072199. http://id.nlm.nih.gov/mesh/2026/D000072199
- ADAM12 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21113786