Structured Summary
Abstract
A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE 76 and VALINE 77 to its functional form, as well as several other CELL SURFACE PROTEINS to their soluble forms, including AMYLOID BETA-PROTEIN PRECURSOR and PRION PROTEIN.
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Classification
Broader headings
Related Concepts
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Synonyms
8 entry terms
- ADAM-10 Protein
- CD156c Antigen
- CD156w Antigen
- Disintegrin and Metalloproteinase Domain-Containing Protein 10
- ADAM 10 Protein
- Antigen, CD156c
- Antigen, CD156w
- Disintegrin and Metalloproteinase Domain Containing Protein 10
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- ADAM Proteins (2004-2016)
- Amyloid Precursor Protein Secretases (2007-2016)
- Membrane Proteins (2004-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. ADAM10 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000072197. http://id.nlm.nih.gov/mesh/2026/D000072197
- ADAM10 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21113783