Structured Summary
Abstract
An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
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Classification
Broader headings
Related Concepts
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See Also
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Synonyms
31 entry terms
- AAA Domains
- AAA Modules
- AAA+ Domain
- AAA+ Modules
- AAA Module
- AAA+ Domains
- AAA+ Module
- Domain, AAA
- Domain, AAA+
- Domains, AAA
- Domains, AAA+
- Module, AAA
- Module, AAA+
- Modules, AAA
- Modules, AAA+
- A-Loop
- P-Loop
- Walker A Motif
- Walker B Motif
- Walker Motif
- Walker Motifs
- A Loop
- A Motif, Walker
- A-Loops
- B Motif, Walker
- Motif, Walker
- Motif, Walker A
- Motif, Walker B
- Motifs, Walker
- P Loop
- P-Loops
MeSH Record
Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Amino Acid Sequence (1990-2017)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. AAA Domain. Medical Subject Headings (MeSH). 2026. Unique ID D000074182. http://id.nlm.nih.gov/mesh/2026/D000074182
- AAA Domain. In: Wikidata. https://www.wikidata.org/wiki/Q24781186