Chemicals and Drugs

8-Hydroxy-2-(di-n-propylamino)tetralin

A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.

Chemical Identity

Chemical Information

Molecular Formula
C16H25NO
Molecular Weight
247.38 g/mol
CAS Registry No.
78950-78-4
IUPAC Name
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
InChIKey
ASXGJMSKWNBENU-UHFFFAOYSA-N
SMILES
CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O
MeSH Unique ID
D017371
Source
PubChem CID 1220

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 8-OH-DPAT
  • 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide
  • 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (+-)-Isomer
  • 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (R)-Isomer,
  • 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (S)-Isomer,
  • 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrochloride, (R)-Isomer,
  • 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrochloride, (S)-Isomer
  • 8-Hydroxy-2-(di-n-propylamino)tetralin, (+-)-Isomer
  • 8-Hydroxy-2-(di-n-propylamino)tetralin, (R)-Isomer
  • 8-Hydroxy-2-(di-n-propylamino)tetralin, (S)-Isomer

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

93; was 8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN (NM) 1982-92

MeSH Record

Previous Indexing

  • Tetrahydronaphthalenes (1982-1992)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.638.960.400w
  2. D04w.615w.638.960.400w

AMA Style

References

  1. National Library of Medicine. 8-Hydroxy-2-(di-n-propylamino)tetralin. Medical Subject Headings (MeSH). 2026. Unique ID D017371. http://id.nlm.nih.gov/mesh/2026/D017371
  2. 8-Hydroxy-2-(di-n-propylamino)tetralin. In: Wikipedia. https://en.wikipedia.org/wiki/8-OH-DPAT
  3. 8-Hydroxy-2-(di-n-propylamino)tetralin. In: Wikidata. https://www.wikidata.org/wiki/Q4644282
  4. 8-Hydroxy-2-(di-n-propylamino)tetralin. In: PubChem Compound. CID 1220. https://pubchem.ncbi.nlm.nih.gov/compound/1220