Chemicals and Drugs

8-Hydroxy-2'-Deoxyguanosine

Common oxidized form of deoxyguanosine in which C-8 position of guanine base has a carbonyl group.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Common oxidized form of deoxyguanosine in which C-8 position of guanine base has a carbonyl group.

Chemical Identity

Chemical Information

Molecular Formula
C10H13N5O5
Molecular Weight
283.24 g/mol
CAS Registry No.
88847-89-6
IUPAC Name
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,7-dihydropurine-6,8-dione
InChIKey
HCAJQHYUCKICQH-VPENINKCSA-N
SMILES
C1[C@@H]([C@H](O[C@H]1N2C3=C(C(=O)NC(=N3)N)NC2=O)CO)O
MeSH Unique ID
D000080242
Source
PubChem CID 135440064

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

32 entry terms
  • 2'-Deoxy-8-Hydroxyguanosine
  • 2'-Deoxy-8-Oxoguanosine
  • 8-Hydroxydeoxyguanosine
  • 8-OH-dG
  • 8-OHdG
  • 8-Oxo-2'-Deoxyguanosine
  • 8-Oxo-Deoxyguanosine
  • 8-oxo-dG
  • 8-oxo-dGuo
  • 8-oxodG
  • 8-oxodGuo
  • 8OHdG
  • 2' Deoxy 8 Hydroxyguanosine
  • 2' Deoxy 8 Oxoguanosine
  • 8 Hydroxy 2' Deoxyguanosine
  • 8 Hydroxydeoxyguanosine
  • 8 Oxo 2' Deoxyguanosine
  • 8 Oxo Deoxyguanosine
  • 2'-Deoxy-7,8-Dihydro-8-Oxoguanosine
  • 2'-Deoxy-8-Oxo-7,8-Dihydroguanosine
  • 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine
  • 7-Hydro-8-Oxodeoxyguanosine
  • 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine
  • 8-Oxo-7,8-Dihydrodeoxyguanosine
  • 8-Oxo-7-Hydrodeoxyguanosine
  • 2' Deoxy 7,8 Dihydro 8 Oxoguanosine
  • 2' Deoxy 8 Oxo 7,8 Dihydroguanosine
  • 7 Hydro 8 Oxodeoxyguanosine
  • 7,8 Dihydro 8 Oxo 2' Deoxyguanosine
  • 8 Oxo 7 Hydrodeoxyguanosine
  • 8 Oxo 7,8 Dihydro 2' Deoxyguanosine
  • 8 Oxo 7,8 Dihydrodeoxyguanosine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2020(1985)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.759.590.454w.240w.500w
  2. D13.570w.230w.360w.500w
  3. D13.570w.583.454w.240w.500w

AMA Style

References

  1. National Library of Medicine. 8-Hydroxy-2'-Deoxyguanosine. Medical Subject Headings (MeSH). 2026. Unique ID D000080242. http://id.nlm.nih.gov/mesh/2026/D000080242
  2. 8-Hydroxy-2'-Deoxyguanosine. In: Wikipedia. https://en.wikipedia.org/wiki/8-Oxo-2%27-deoxyguanosine
  3. 8-Hydroxy-2'-Deoxyguanosine. In: Wikidata. https://www.wikidata.org/wiki/Q270154
  4. 8-Hydroxy-2'-Deoxyguanosine. In: PubChem Compound. CID 135440064. https://pubchem.ncbi.nlm.nih.gov/compound/135440064