Chemicals and Drugs

6-Cyano-7-nitroquinoxaline-2,3-dione

A potent excitatory amino acid antagonist with a preference for non-NMDA iontropic receptors. It is used primarily as a research tool.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent excitatory amino acid antagonist with a preference for non-NMDA iontropic receptors. It is used primarily as a research tool.

Chemical Identity

Chemical Information

Molecular Formula
C9H4N4O4
Molecular Weight
232.15 g/mol
CAS Registry No.
115066-14-3
IUPAC Name
7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
InChIKey
RPXVIAFEQBNEAX-UHFFFAOYSA-N
SMILES
C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N
MeSH Unique ID
D018750
Source
PubChem CID 3721046

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile
  • 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline
  • CNQX
  • 6 Cyano 2,3 dihydroxy 7 nitroquinoxaline
  • 6 Cyano 7 nitroquinoxaline 2,3 dione
  • FG-9065
  • FG 9065
  • FG9065

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

95; was FG 9065 (NM) 1988-94

MeSH Hierarchy

Tree Number

  1. D03w.633.100.857.160w

AMA Style

References

  1. National Library of Medicine. 6-Cyano-7-nitroquinoxaline-2,3-dione. Medical Subject Headings (MeSH). 2026. Unique ID D018750. http://id.nlm.nih.gov/mesh/2026/D018750
  2. 6-Cyano-7-nitroquinoxaline-2,3-dione. In: Wikipedia. https://en.wikipedia.org/wiki/CNQX
  3. 6-Cyano-7-nitroquinoxaline-2,3-dione. In: Wikidata. https://www.wikidata.org/wiki/Q4386534
  4. 6-Cyano-7-nitroquinoxaline-2,3-dione. In: PubChem Compound. CID 3721046. https://pubchem.ncbi.nlm.nih.gov/compound/3721046