Chemicals and Drugs

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid

An inhibitor of anion conductance including band 3-mediated anion transport.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An inhibitor of anion conductance including band 3-mediated anion transport.

Chemical Identity

Chemical Information

Molecular Formula
C16H10N2O6S4
Molecular Weight
454.5 g/mol
CAS Registry No.
53005-05-3
IUPAC Name
5-isothiocyanato-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
InChIKey
YSCNMFDFYJUPEF-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1N=C=S)S(=O)(=O)O)C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)O
MeSH Unique ID
D017878
Source
PubChem CID 40600

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

2 entry terms
  • 4,4'-Diisothiocyano-2,2'-Stilbene Disulfonic Acid
  • DIDS

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2001(1994); use DIDS (NM) 1977-93

MeSH Record

Previous Indexing

  • SITS/analogs & derivatives (1981-1993)
  • Stilbenes (1977-1980)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.389.150w.700w.200w
  2. D02w.500.375w.125w
  3. D02w.886w.250w.125w

AMA Style

References

  1. National Library of Medicine. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D017878. http://id.nlm.nih.gov/mesh/2026/D017878
  2. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/DIDS
  3. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q4036893
  4. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid. In: PubChem Compound. CID 40600. https://pubchem.ncbi.nlm.nih.gov/compound/40600