Chemicals and Drugs

(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride

A drug that selectively activates certain subclasses of muscarinic receptors and also activates postganglionic nicotinic receptors. It is commonly used experimentally to distinguish muscarinic receptor subtypes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug that selectively activates certain subclasses of muscarinic receptors and also activates postganglionic nicotinic receptors. It is commonly used experimentally to distinguish muscarinic receptor subtypes.

Chemical Identity

Chemical Information

Molecular Formula
C14H18Cl2N2O2
Molecular Weight
317.2 g/mol
CAS Registry No.
55-45-8
IUPAC Name
4-[(3-chlorophenyl)carbamoyloxy]but-2-ynyl-trimethylazanium chloride
InChIKey
CXFZFEJJLNLOTA-UHFFFAOYSA-N
SMILES
C[N+](C)(C)CC#CCOC(=O)NC1=CC(=CC=C1)Cl.[Cl-]
MeSH Unique ID
D008455
Source
PubChem CID 5926

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • McN A-343
  • McN-A-343
  • McN-A343
  • McNeil A 343
  • A 343, McNeil
  • McN A 343
  • McN A343
  • McNA343

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

McN stands for McNeil (a pharmaceut co)

MeSH Record

History Note

2005(1975)

MeSH Record

Previous Indexing

  • Alkynes (1972-1974)
  • Ammonium Compounds (1968-1974)
  • Carbamates (1968-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.877.674.033
  2. D02w.455w.326.397w.325
  3. D02w.675w.276.210

AMA Style

References

  1. National Library of Medicine. (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride. Medical Subject Headings (MeSH). 2026. Unique ID D008455. http://id.nlm.nih.gov/mesh/2026/D008455
  2. (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride. In: Wikidata. https://www.wikidata.org/wiki/Q27083728
  3. (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride. In: PubChem Compound. CID 5926. https://pubchem.ncbi.nlm.nih.gov/compound/5926