Structured Summary
Abstract
QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.
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Synonyms
11 entry terms
- 4-Oxoquinoline
- 4-Oxoquinolines
- 4-Quinolinone
- 4-Quinolinones
- 4-Quinolone
- 4 Oxoquinoline
- 4 Oxoquinolines
- 4 Quinolinone
- 4 Quinolinones
- 4 Quinolone
- 4 Quinolones
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Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2004
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AMA Style
References
- National Library of Medicine. 4-Quinolones. Medical Subject Headings (MeSH). 2026. Unique ID D042462. http://id.nlm.nih.gov/mesh/2026/D042462
- 4-Quinolones. In: Wikipedia. https://en.wikipedia.org/wiki/Quinolone_antibiotic
- 4-Quinolones. In: Wikidata. https://www.wikidata.org/wiki/Q13669486