Chemicals and Drugs

4-1BB Ligand

A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • 4-1BBL Protein
  • CD137 Ligand
  • Tumor Necrosis Factor (Ligand) Superfamily, Member 9
  • Tumor Necrosis Factor Ligand Superfamily Member 9
  • 4 1BB Ligand
  • 4 1BBL Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1998)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. 4-1BB Ligand. Medical Subject Headings (MeSH). 2026. Unique ID D053330. http://id.nlm.nih.gov/mesh/2026/D053330
  2. 4-1BB Ligand. In: Wikipedia. https://en.wikipedia.org/wiki/TNFSF9
  3. 4-1BB Ligand. In: Wikidata. https://www.wikidata.org/wiki/Q21124647