Structured Summary
Abstract
Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
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Synonyms
3 entry terms
- 3T3 Cell
- Cell, 3T3
- Cells, 3T3
MeSH Record
Aspects Covered
15 allowable subheadings
Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.
MeSH Record
Indexing Annotation
almost always NIM with no subheadings; check ANIMALS & MICE; do not routinely add FIBROBLASTS or EMBRYO, MAMMALIAN
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History Note
1992
MeSH Record
Previous Indexing
- Cell Line (1966-1991)
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AMA Style
References
- National Library of Medicine. 3T3 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D016475. http://id.nlm.nih.gov/mesh/2026/D016475
- 3T3 Cells. In: Wikipedia. https://en.wikipedia.org/wiki/3T3_cells
- 3T3 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q68153243