Chemicals and Drugs

3-Hydroxyacyl CoA Dehydrogenases

Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.

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Classification

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Synonyms

6 entry terms
  • beta-Hydroxyacyl Dehydrogenases
  • 3 Hydroxyacyl CoA Dehydrogenases
  • CoA Dehydrogenases, 3-Hydroxyacyl
  • Dehydrogenases, 3-Hydroxyacyl CoA
  • Dehydrogenases, beta-Hydroxyacyl
  • beta Hydroxyacyl Dehydrogenases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

78

MeSH Record

Previous Indexing

  • Alcohol Oxidoreductases (1966-1977)
  • Coenzyme A (1966-1977)

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References

  1. National Library of Medicine. 3-Hydroxyacyl CoA Dehydrogenases. Medical Subject Headings (MeSH). 2026. Unique ID D015094. http://id.nlm.nih.gov/mesh/2026/D015094
  2. 3-Hydroxyacyl CoA Dehydrogenases. In: Wikipedia. https://en.wikipedia.org/wiki/3-hydroxyacyl-CoA_dehydrogenase
  3. 3-Hydroxyacyl CoA Dehydrogenases. In: Wikidata. https://www.wikidata.org/wiki/Q24772904