Chemicals and Drugs

3-Deazauridine

4-Hydroxy-1-(beta-D-ribofuranosyl)-2-pyridinone. Analog of uridine lacking a ring-nitrogen in the 3-position. Functions as an antineoplastic agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

4-Hydroxy-1-(beta-D-ribofuranosyl)-2-pyridinone. Analog of uridine lacking a ring-nitrogen in the 3-position. Functions as an antineoplastic agent.

Chemical Identity

Chemical Information

Molecular Formula
C10H13NO6
Molecular Weight
243.21 g/mol
CAS Registry No.
23205-42-7
IUPAC Name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxypyridin-2-one
InChIKey
CBOKZNLSFMZJJA-PEBGCTIMSA-N
SMILES
C1=CN(C(=O)C=C1O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
MeSH Unique ID
D015092
Source
PubChem CID 54684286

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • 4-Hydroxy-1-(beta-D-Ribopentofuranosyl)-2-Pyridone
  • 3 Deazauridine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

an antineoplastic antimetabolite

MeSH Record

History Note

91(75); was see under URIDINE 1975-90

MeSH Record

Previous Indexing

  • Pyridones (1973-1974)
  • Uridine (1972-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. 3-Deazauridine. Medical Subject Headings (MeSH). 2026. Unique ID D015092. http://id.nlm.nih.gov/mesh/2026/D015092
  2. 3-Deazauridine. In: Wikidata. https://www.wikidata.org/wiki/Q27254037
  3. 3-Deazauridine. In: PubChem Compound. CID 54684286. https://pubchem.ncbi.nlm.nih.gov/compound/54684286