Chemicals and Drugs

2-Acetolactate Mutase

An enzyme involved in the biosynthesis of isoleucine and valine. It converts 2-acetolactate into 3-hydroxy-2-oxo-isovalerate. Also acts on 2-hydroxy-2-acetobutyrate to form 2-hydroxy-2-oxo-3-methylvalerate. EC 5.4.99.3.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme involved in the biosynthesis of isoleucine and valine. It converts 2-acetolactate into 3-hydroxy-2-oxo-isovalerate. Also acts on 2-hydroxy-2-acetobutyrate to form 2-hydroxy-2-oxo-3-methylvalerate. EC 5.4.99.3.

MeSH Record

Classification

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MeSH Record

Synonyms

8 entry terms
  • 2-Acetohydroxy-3-Ketoacid Isomeroreductase
  • Acetohydroxy Acid Reductoisomerase
  • 2 Acetohydroxy 3 Ketoacid Isomeroreductase
  • 2 Acetolactate Mutase
  • Acid Reductoisomerase, Acetohydroxy
  • Isomeroreductase, 2-Acetohydroxy-3-Ketoacid
  • Mutase, 2-Acetolactate
  • Reductoisomerase, Acetohydroxy Acid

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(75); was see under ISOMERASES 1975-90

MeSH Record

Previous Indexing

  • Hydroxybutyrates (1973-1974)
  • Isomerases (1973-1974)
  • Lactates (1973-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. 2-Acetolactate Mutase. Medical Subject Headings (MeSH). 2026. Unique ID D015072. http://id.nlm.nih.gov/mesh/2026/D015072
  2. 2-Acetolactate Mutase. In: Wikipedia. https://en.wikipedia.org/wiki/2-acetolactate_mutase
  3. 2-Acetolactate Mutase. In: Wikidata. https://www.wikidata.org/wiki/Q4596924