Chemicals and Drugs

19-Iodocholesterol

19-Iodocholest-5-en-3 beta-ol. A cholesterol derivative usually substituted with radioactive iodine in the 19 position. The compound is an adrenal cortex scanning agent used in the assessment of patients suspected of having Cushing's syndrome, hyperaldosteronism, pheochromocytoma and adrenal remnants following total adrenalectomy.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

19-Iodocholest-5-en-3 beta-ol. A cholesterol derivative usually substituted with radioactive iodine in the 19 position. The compound is an adrenal cortex scanning agent used in the assessment of patients suspected of having Cushing's syndrome, hyperaldosteronism, pheochromocytoma and adrenal remnants following total adrenalectomy.

Chemical Identity

Chemical Information

Molecular Formula
C27H45IO
Molecular Weight
512.5 g/mol
CAS Registry No.
37414-03-2
IUPAC Name
(3S,8S,9S,10S,13R,14S,17R)-10-(iodomethyl)-13-methyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey
FIOAEFCJGZJUPW-FTLVODPJSA-N
SMILES
C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)CI)C
MeSH Unique ID
D015071
Source
PubChem CID 21150757

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

1 entry terms
  • 19 Iodocholesterol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under CHOLESTEROL 1979-90

MeSH Record

Previous Indexing

  • Cholesterol (1968-1974) /AA (1975-1978)
  • Iodine Radioisotopes (1966-1978)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.247.222w.284w.510w
  2. D04w.210.500w.247.808w.197w.580w
  3. D10w.570w.938w.208w.627w

AMA Style

References

  1. National Library of Medicine. 19-Iodocholesterol. Medical Subject Headings (MeSH). 2026. Unique ID D015071. http://id.nlm.nih.gov/mesh/2026/D015071
  2. 19-Iodocholesterol. In: Wikipedia. https://en.wikipedia.org/wiki/Iodocholesterol
  3. 19-Iodocholesterol. In: Wikidata. https://www.wikidata.org/wiki/Q4557701
  4. 19-Iodocholesterol. In: PubChem Compound. CID 21150757. https://pubchem.ncbi.nlm.nih.gov/compound/21150757