Chemicals and Drugs

1-Deoxynojirimycin

An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.

Chemical Identity

Chemical Information

Molecular Formula
C6H13NO4
Molecular Weight
163.17 g/mol
CAS Registry No.
19130-96-2
IUPAC Name
(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
InChIKey
LXBIFEVIBLOUGU-JGWLITMVSA-N
SMILES
C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O
MeSH Unique ID
D017485
Source
PubChem CID 29435

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 1 Deoxynojirimycin
  • 1,5-Deoxy-1,5-imino-D-mannitol
  • 1,5-Dideoxy-1,5-imino-D-mannitol
  • 1-Deoxymannojirimycin
  • 1-Deoxynojirimycin Hydrochloride
  • Bay n 5595
  • Moranoline
  • 1 Deoxymannojirimycin
  • 1 Deoxynojirimycin Hydrochloride

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

93; was DEOXYNOJIRIMYCIN (NM) 1981-92; 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL was NM 1984-92

MeSH Record

Previous Indexing

  • Glucosamine/analogs & derivatives (1981-1992)

MeSH Hierarchy

Tree Numbers

  1. D02w.491w.567w.500.033w
  2. D03w.132w.014w
  3. D03w.383.621.300.033w
  4. D09w.553w.500.033w

AMA Style

References

  1. National Library of Medicine. 1-Deoxynojirimycin. Medical Subject Headings (MeSH). 2026. Unique ID D017485. http://id.nlm.nih.gov/mesh/2026/D017485
  2. 1-Deoxynojirimycin. In: Wikipedia. https://en.wikipedia.org/wiki/1-Deoxynojirimycin
  3. 1-Deoxynojirimycin. In: Wikidata. https://www.wikidata.org/wiki/Q15274561
  4. 1-Deoxynojirimycin. In: PubChem Compound. CID 29435. https://pubchem.ncbi.nlm.nih.gov/compound/29435